The European network
for cell migration studies
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 642866.
Workshop 4: Mid consolidation phase II
1 week; target groups: all ESRs/partners and selected cooperation partners/interested third parties upon recommendation by participating beneficiaries and partner organisations
The workshop will build on the previous workshops. Besides enhancing cross-sectoral knowledge and skills, it will aim to train ESRs in complementary skills. Each of the following topics is relevant to InCeM's main goals and will be the subject of a half-day or full-day programme that includes a presentation of pertinent ESR results:
Migrating primary keratinocyte with labelled cell adhesions. Based on a fine tuned regulation adhesion structures are continuously formed, modified and finally disassembled.
Primary keratinocytes apply traction forces upon migration. Using fluorescent fusion proteins (GFP-vinculin), adhesion structures can be visualized. Those sites are used by the cell for cell force transmission to the underlying substrate. In case those substrates are elastic, forces cause deformation fields that can be visualized using marker particles.
A typical example of the application of the evolving surface finite element method when solving partial differential equations of reaction-diffusion type on an evolving closed surface representing an evolving tumour.
A typical example of the application of the evolving surface finite element method when solving partial differential equations of reaction-diffusion type on an evolving open surface.
Time-lapse recordings of HK18-YFP fluorescence (left) of a migrating EK18-1 cell displaying multiple emerging KFPs in the proceeding lamellipodium. (Kölsch et al., 2010)
Induction of cell border dynamics through UV-light induced activation of pa-rac.
Last update: 19.12.2017