The European network
for cell migration studies
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 642866.
As the InCeM project is now past its 30th month, a new public deliverable has been compiled within Work Package 6 “Communication and dissemination” to report on the project’s progress. In this deliverable, D6.1 “Communication I”, you can read up on all the different publications and presentations of scientific data which have been produced in the context of the InCeM project so far! You can get an overview of the different topics, researchers, and various conferences that they attended in their capacity as InCeM researchers.
Please find attached the next InCeM newsletter (edition May 2017) including some updates
The symposium was organized by Rudolf Leube. It brought together leading experts in the field with InCeM groups from RWTH Aachen University and Forschungszentrum Jülich.
Group photo of organizers and speakers (from left to right): Prof. Horst Fischer, Prof. Andreas Ludwig, Prof. Rudolf Leube, Prof. Reinhard Windoffer, Barbara Nöthel, Prof. Dennis Discher, Prof. Rudolf Merkel, Prof. Lorenzo Moroni, Dr. Laura De Laporte, Prof. Wolfgang Wagner, PD Petra Mela, Dr. Andreas Blaeser, Dr. Brigitte Küppers.
Migrating primary keratinocyte with labelled cell adhesions. Based on a fine tuned regulation adhesion structures are continuously formed, modified and finally disassembled.
Primary keratinocytes apply traction forces upon migration. Using fluorescent fusion proteins (GFP-vinculin), adhesion structures can be visualized. Those sites are used by the cell for cell force transmission to the underlying substrate. In case those substrates are elastic, forces cause deformation fields that can be visualized using marker particles.
A typical example of the application of the evolving surface finite element method when solving partial differential equations of reaction-diffusion type on an evolving closed surface representing an evolving tumour.
A typical example of the application of the evolving surface finite element method when solving partial differential equations of reaction-diffusion type on an evolving open surface.
Time-lapse recordings of HK18-YFP fluorescence (left) of a migrating EK18-1 cell displaying multiple emerging KFPs in the proceeding lamellipodium. (Kölsch et al., 2010)
Induction of cell border dynamics through UV-light induced activation of pa-rac.
13. - 17.2.2017
InCeM Members at the Leuven Institute for Ireland in Europe.
When you are interested in attending this workshop klick here
Check out this website, if you have questions related to our Marie Curie Action InCeM. For example, they provide the following explanation of the difference between a short visit and a secondment:
With regard to short visits, these are permitted as well, as long as the concept of short visit is kept. We would like to refrain from defining a time frame of 1-2 weeks because we want to avoid the next question “what about 2 weeks and 1 day - visits”.
The key point is that the short visits should clearly not be secondments. Secondments have a clear impact on the project, are planned before, and have a particular scope – for example, without the secondment the final results of the project would not be possible. A short visit on the other hand will have a limited impact and could be something that arises during the fellowship, so mentioning it in the proposal is not always necessary.
(Answer provided by REA)
Johan Kreuger from InCeM partner organisation Uppsala University in Sweden has been in the news. Read the article about a recent study that shows how smartphones can be used to make movies of living cells, without the need for expensive equipment. The study makes it possible for laboratories around the world to do the same thing.
We are happy to announce another publication of partner ANDOR in the Irish Machine Vision and Image Processing Conference Proceedings 2016 (p. 35-42). Thanks to Katerina for her contribution!
"Optics, Algos & Ice"
Symposium on Image
Analysis of Cells in Tissue
Our partner organisation TissueGnostics is organizing the Optics, Algos and Ice symposium from November 17th to November 20th 2016 in Obergurgl, Tyrol, Austria. The focus of this symposium is on Advanced Digital Microscopy and Image Analysis, its role in revolutionizing clinical diagnostics and in implementing the personalized medicine concept.
We congratulate Nadieh Kuijpers on the award for her poster "Keratin and actin dynamics during epithelial cell migration" that she presented during the Heraeus-Seminar "Cellular Dynamics". The meeting took place in the Physikzentrum Bad Honnef, Germany, from September 4-7, 2016.
We are happy to announce the upcoming Subgroup meeting 3 at Uniklinik RWTH Aachen (UKA) on 1st September, 2016 with focus on the discussion of results between the experimental and the image processing groups. The meeting will begin with experimental part presented by 5 ESRs from UKA, JUELICH, IBIDI and UDE followed by 3 ESRs from SCCH and ANDOR who will take over the image processing part.
Looking forward to make productive collaborations!
We are happy to announce that the first InCeM publication has been accepted and is now online. Congratulations to our project partners ibidi GmbH and University of Sussex!
Advanced Microscopy & Image Analysis - tools for molecular pathology and personalized medicine at the Obergurgl University Center, Tyrol, Austria
University of Nairobi Vice Chancellor Peter Mbithi presented a gold medal to Victor Juma. He was recognized as the best male overall student with the highest proficiency in both the academic and extra-curricular activities at the institution. The gold medal is a courtesy of the Gandhi Smarak Nidhi Trustee Fund.
One obligation within our project activities is to ensure a good communication and dissemination of project results. As InCeM mainly consists of young scientists, our Early Stage Researchers started a Facebook page in order to share the project with a broader audience. This communication media is commonly accepted under young people and whenever we have anything to share with the world, we will post the news on Facebook.
Please like us via https://www.facebook.com/IntegratedCEM
University of Sussex
The Department is delighted to announce that a 4-year EU-MSCA-ITN-2014-ETN - Marie Sklodowska-Curie Innovative Training Network (ITN-ETN) grant has been successfully awarded to support Research Training Network on Integrated Component Cycling in Epithelial Cell Motility (InCeM). The grant, worth 3.8 million euros over the four year period is coordinated by Professor Rudolf Leube of RWTH Aachen University in Germany and here at Sussex, Dr Anotida Madzvamuse in Mathematics is one of the 11 key partners from 6 European countries and Israel. In addition, 17 associated partners support the network making it one of the largest ITN. Two out of 15 PhD studentships will be hosted and based at Sussex.
InCeM is focused on cell migration, which is essential for vital processes such as tissue formation, wound healing and tissue invasion during carcinogenesis. It aims to visualize morphological, biochemical and physical processes of cell motility to integrate these data into multi-scale models with the goal to deliberately tune motile behavior in relation to disease. InCeM provides an international and highly interdisciplinary framework of collaborators from academia and industry with core expertise in medicine, biology, biochemistry, image analysis, modelling and engineering.
InCeM Members at the Isaac Newton Institute in Cambridge during the 2. InCeM Workshop
The kick-off meeting was attended by representatives of all beneficiaries and several partner organisations with participants from six European countries, Israel, Canada and Singapore. To get to know each other and each other's work each partner provided a ~20 minute presentation on the first day. These introductions set the stage for intense discussions. The late afternoon was reserved for learning about EU rules and regulations, which were competently showcased by our project manager Christine Kempchen. After a "night in the city" we skype interviewed almost 30 fellowship candidates that had been selected from more than 330 applicants. Rigorous organisation helped us to stay on time and to come up with recommendations for each project. The final meeting and subsequent excursion to the city with a performance of Mendelssohn's "Elias" in the Aachen cathedral completed the meeting leaving all of us with a feeling of exciting anticipation for the future of InCeM. (Impressions)
InCeM website starts.
GRANT Agrement signed.
With the signing the Grant Agrement InCeM will start as planned in January 2015.
Last update: 29.08.2017